Wow, she looks awesome! What kind of sci-fi world is she a part of? My experience with sci-fi mainly begins and ends with Star Wars and Star Trek... anyhow, I love her face and constume! Her expressions are very fun, too! Does she have a name?
Heh well I've never tried myself, but from what I've gathered from following a bunch of them over the years, the most important thing is planning. The worst thing you can do is dive headfirst into it without having the details down - that means having a plot summary down before you start, having all the character designs at a stage where you're happy with them and so on. I've seen a lot of webcomics where the artist rushes into it and ends up overwhelmed by everything.
Basically I'd say just take your time and get comfortable with everything before you get started and release it into the wild, there's no rush C: Oh also be prepared for the sheer amount of time involved - for a lot of comics even just keeping up a weekly schedule takes hours of work for every page, which might get difficult if you've got a lot of other stuff going on.
But yeah I think you should go for it if you can find the time, give it a try